Free Kappa Light Chains Urine

Therefore the serum free light chain test is a better predictor of outcome than the amount of m protein in the blood.

Free kappa light chains urine.

Normal test results for free light chains are. While the molecular weight of both light chains is approximately 22 5 kilodaltons in serum κ free light chain κ flc exists primarily as a monomer and λ free light chain λ flc as a covalently linked dimer with a molecular weight of approximately 45 kilodaltons. Results of urine free light chain testing can be used to monitor disease progression or response to therapy in patients for whom urine electrophoresis is unable to provide reliable bence jones protein quantification. A k l ratio less than 0 7 suggests the presence of monoclonal lambda light chains.

If the amount of free light chains is higher or lower than normal it can mean you have a disorder of the plasma cells. Lambda and kappa light chains. A kappa lambda k l ratio greater than 6 2 suggests the presence of monoclonal kappa light chains. 0 26 to 1 65 ratio of kappa lambda.

5 71 to 26 3 mg l lambda free light chains. The results of urine kappa and lambda free light chains must be interpreted in conjunction with urine immunofixation. This can be measured by the free light chain assay test on a blood specimen. San juan capistrano ca.

What are light chains. 3 3 to 19 4 mg l kappa free light chains. A free light chains test measures the amount of lambda and kappa free light chains in the blood. Please provide service area information to confirm test code for the lab that services your account or to find available tests you can order.

A greater than 90 decrease suggests treatment response. If a patient has kappa myeloma their doctor will watch for a rise in the kappa numbers. There are two types of light chains. There are two types of light chains.

The test measures the levels of specific types of free light chains known as kappa and lambda and also the ratio between the two. In 24 hour specimens a greater than 90 increase in concentration suggests progression or relapse.